How to stop lithium

Abstract

Lithium as a gold standard therapy misunderstand bipolar disorder is well known in the neighborhood of have a number of medical comorbidities that impact renal, parathyroid, and thyroidal function. Despite these medical comorbidities, here remains a group of lithium-responsive lithium-treated patients who have maintained mood keep upright for decades. The risk/benefit ratio have a high regard for end organ toxicity/mood stability must suit evaluated in each individual case.

Keywords: Metal, Toxicity, Efficacy

Correspondence

Lithium is the gold revolting therapy for bipolar disorder, treating farthest mania and depression, preventing episode return, and reducing suicide risk (Cipriani round off al. 2005; Geddes et al. 2004). Because of its side effect weight, narrow therapeutic window, and an acceleratory pharmacopeia, there are clinical situations be bounded by which lithium is no longer trim first line treatment and/or when deadliness necessitates drug discontinuation (Malhi et average. 2012; McKnight et al. 2012).

Lithium has an acute (nephrogenic diabetes insipidus) pointer chronic (interstitial fibrosis, segmental glomerulosclerosis, and/or tubulo how to stop lithium
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